Digital Image Processing Lab

Department of Radiology, University of Michigan

MIAMI Fuse: Mutual Information for Automatic Multimodality Image Fusion

Automated Multimodality Fusion via MI:
Accuracy & Clinical Versatility

The QuickTime movies referenced below were prepared as figures for a manuscript that appears in Medical Image Analysis, "Demonstration of accuracy and clinical versatility of mutual information for automatic multimodality image fusion using affine and thin plate spline warped geometric deformations".

The full paper is available at the Medical Image Analysis Web Site.

The complete bibliographic citation is also available.

QuickTime Movies

To view a movie of this work, select an underlined link below. Figure references below correspond to the references in the MIA article which are snapshots of the complete movies that are viewable here.
Or to view them in a separate window, press
(This may be necessary on some browsers to allow you to read the explanatory text in this window [see below] while simultaneously viewing the movie in the other.)

Compressed versions of the movies were generated by omitting alternating frames.

Figure 4, Part 4: 5.5Mb QuickTime movie or 2.6Mb compressed version
Axial slices through the thorax phantom's PET/CT registration are shown using CT as reference to demonstrate partial volume registration quality. The color composite combines CT data in gray and PET data in red. For PET a combined contrast window has been applied to demonstrate both low and high concentrations without associated blooming of the high concentrations.

Figure 4, Part 5: 4.5Mb QuickTime movie or 2.8Mb compressed version
Axial slices of the registration of a PET cerebral blood flow study and a postsurgical coronal MRI study are shown using MRI as reference. The color composite combines MRI in gray and PET in pseudocolor.

Figure 4, Part 6: 4.3Mb QuickTime movie or 1.9Mb compressed version
Axial slices of the full affine thorax registration are shown using the downsized (256 x 256) CT as reference. In the color composite, CT is shown in gray using a lung window contrast setting, and PET is shown in pseudocolor.

Figure 4, Part 7: 5.3Mb QuickTime movie or 1.9Mb compressed version
Axial slices of a PET/CT thin plate spline warped registration of a patient's thorax are shown using the downsized CT as reference. In the color composite, CT is displayed in gray using a combined lung and soft tissue window contrast setting, and PET is shown in pseudocolor.

Figure 4, Part 8: 3.5Mb QuickTime movie or 1.1Mb compressed version
Axial slices of a SPECT/CT, rotate-translate registration are shown using the downsized CT as reference. In the color composite, CT is displayed in gray using a soft tissue window constrast setting, and PET is shown in pseudocolor. In addition to the expected concentrations in the liver, spleen and kidneys, note the uptake in the lymph nodes which reside near the descending aorta and the iliac arteries below the aorta's bifurcation.

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